Is deep brain stimulation useful in Lance–Adams syndrome?

Lance–Adams syndrome (LAS) is a chronic post-hypoxic myoclonus that occurs after successful cardiopulmonary resuscitation. Although many drugs are available to treat this condition, the underlying mechanism of disease yet be understood. Deep brain stimulation (DBS) has been attempted and proven partially in treating LAS several cases. Here, we present 40-year-old woman who developed subsequent arrest (CPA) occurred her first cesarean delivery at age 26 years. The patient underwent implantation bilateral globus pallidus interna (GPi)-DBS about 14 years onset. Regarding Unified Myoclonus Rating Scale (UMRS), 8% 20% improvements were observed action resting myoclonus, respectively, with high-frequency as result 3-year follow-up study. In case, neuromodulation therapy applied hypoxia-causing was not sufficiently beneficial.